Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody | Boster M30950-2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody

catalog :

M30950-2

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

GBG-5

reactivity :

human

application :

western blot, immunohistochemistry

product information

SKU :

M30950-2

Product Name :

Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

GBG-5

Host :

Rabbit

Reactivity :

Human

Application(s) :

IHC, WB

Application Details :

WB 1:1000-1:2000 .IHC 1:50-1:200

Description :

Boster Bio Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody catalog # M30950-2. Tested in IHC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

EPCAM

Uniprot ID :

P16422

Immunogen :

A synthesized peptide derived from human EpCAM

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Epithelial cell adhesion molecule

Synonyms :

Epithelial cell adhesion molecule; Ep-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; CD326; EPCAM; GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1;

Molecular Weight :

34932 MW

Protein Function :

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Subcellular Localization :

Lateral cell membrane ; Single-pass type I membrane protein. Cell junction, tight junction. Colocalizes with CLDN7 at the lateral cell membrane and tight junction.

Tissue Specificity :

Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.

Research Category :

Cell Type Markers, Tags & Cell Markers, Tumor Associated