Anti-Dectin-2 Antibody (Monoclonal, ABM2H28) | Boster M11863 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Dectin-2 Antibody (Monoclonal, ABM2H28)

catalog :

M11863

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ABM2H28

reactivity :

human, mouse

application :

western blot, immunohistochemistry, flow cytometry

product information

sku :

M11863

status :

Enabled

name :

Anti-Dectin-2 Antibody (Monoclonal, ABM2H28)

category name :

Primary Antibodies, Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

CLEC6A

price various sizes :

25ug sample size / $99 100 ug / $299 100 ug+Free HRP Secondary BA1050 / $299 100 ug+Free Biotin Secondary BA1001 / $299

clonality :

Monoclonal

clone number :

ABM2H28

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide.

description :

Monoclonal clone# G2 antibody for CLEC6A detection. Host: Mouse.Size: 100 ug. Tested applications: Flow Cytometry. Reactive species: Human. CLEC6A information: Molecular Weight: 23998 MW; Subcellular Localization: Membrane ; Single-pass type II membrane protein ; Tissue Specificity: Expressed in lung, spleen, lymph node, leukocytes, bone marrow, tonsils and dendritic cells. Strongly expressed in purified monocytes and weakly in B-cells. In peripheral blood cells, preferentially expressed in plasmacytoids rather than myeloids.

short description :

Mouse IgG3 Kappa Monoclonal antibody for CLEC6A detection. Tested with IHC, Flow Cytometry, WB in Mouse, Human. Various direct flourescent conjugates are available for FCM upon request. Please contact us for details.

size :

100 ug

sample size available :

25ug for $99, contact us for details

uniprot id :

Q6EIG7

host :

Mouse

immunogen :

A partial length recombinant Dectin-2 protein (amino acids 70-230).

form :

Liquid

storage :

Store the antibody at 4 C, stable for 6 months. For long-term storage, store at -20 C. Avoid repeated freeze and thaw cycles.

isotype :

IgG3 Kappa

application details :

Western blot analysis, 2-4 ug/ml. Flow Cytometry analysis, 0.5 ug/10^6 cells. Immunohistochemical analysis, 5 ug/ml.

applications :

Flow Cytometry, IHC, WB

reactivity :

Human, Mouse

image labels :

Intracellular flow analysis of Dectin-2 in human PBMC (Lymphocytes) using 0.5 ug/10^6 cells of Dectin-2 antibody (Clone: ABM2H28). Green represents isotype control; red represents anti-Dectin-2 antibody. Goat anti-mouse PE conjugate was used as secondary. Immunohistochemical analysis of Dectin-2 in Renal Cell Carcinoma using Dectin-2 antibody (Clone: ABM2H28) at 5 ug/ml. Western blot analysis of Dectin 2 Anti- Dectin 2 antibody (Clone: ABM2H28) was used at 2 ug/ml on Raw lysate.

research category :

Immunology, Innate Immunity, Macrophage / Inflamm.

synonyms :

C-type lectin domain family 6 member A;C-type lectin superfamily member 10;Dendritic cell-associated C-type lectin 2;DC-associated C-type lectin 2;Dectin-2;CLEC6A;CLECSF10, DECTIN2;

gene full name :

C-type lectin domain family 6 member A

molecular weight :

23998 MW

protein function :

Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9- NF-kappa-B-dependent pathway (By similarity).

subcellular localization :

Membrane ; Single-pass type II membrane protein .

tissue specificity :

Expressed in lung, spleen, lymph node, leukocytes, bone marrow, tonsils and dendritic cells. Strongly expressed in purified monocytes and weakly in B-cells. In peripheral blood cells, preferentially expressed in plasmacytoids rather than myeloids.

protein name :

C-type lectin domain family 6 member A

last modified :

2/6/19 22:57