Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody | Boster M08039 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody

catalog :

M08039

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

FHH-20

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

product information

SKU :

M08039

Product Name :

Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

FHH-20

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IP, IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .IP 1:50

Description :

Boster Bio Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody catalog # M08039. Tested in IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

TPSAB1

Uniprot ID :

Q15661

Immunogen :

A synthesized peptide derived from human Mast Cell Tryptase

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Tryptase alpha/beta-1

Synonyms :

Tryptase alpha/beta-1; Tryptase-1; 3.4.21.59; Tryptase I; Tryptase alpha-1; TPSAB1; TPS1, TPS2, TPSB1;

Molecular Weight :

30515 MW

Protein Function :

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).

Subcellular Localization :

Secreted. Released from the secretory granules upon mast cell activation.

Tissue Specificity :

Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level).

Research Category :

Amino Acid Metabolism, Amino Acids, Cancer, Immunology, Innate Immunity, Macrophage / Inflamm., Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Signal Transduction