Anti-Hu CD103 Purified ITGAE Monoclonal Antibody | Boster M07091-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Hu CD103 Purified ITGAE Monoclonal Antibody

catalog :

M07091-1

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Ber-ACT8

The same clone is also sold as:

BD Biosciences: 561677, 550258, 340945, 550260, 564346, 550259, 340944
Exbio: 1A-670-T100, 1F-670-T100, 1A-670-T025, 1F-670-T025, 11-670-C100, 1P-670-T025, 1P-670-T100, 11-670-C025
OriGene: AM26142FC-N, AM26142AC-N, AM26142PU-N, AM26142RP-N
Novus Biologicals: NBP1-97564
Santa Cruz Biotechnology: sc-19981
Invitrogen: MA5-38699, 11-1037-41, 46-1037-41, 17-1037-42, 46-1037-42
Abnova: MAB15387
BioLegend: 350206, 350218, 350224, 350225, 984806, 350211, 350245, 350215, 350213, 350237, 984804, 350217, 350212, 350250, 350249, 350214, 260330, 260328, 350230, 350210, 350220, 350221, 350244, 350227, 350222, 350240, 350204, 350241, 350238, 350223, 350243, 350235, 350205, 350208, 350209, 350226, 350233, 350248, 350251, 350202, 350229, 350216, 984808, 350228, 350247, 350246, 350231, 350239, 350203

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M07091-1

Product Name :

Anti-Hu CD103 Purified ITGAE Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

Ber-ACT8

Host :

Mouse

Reactivity :

Human, Monkey

Application(s) :

Flow Cytometry, IP, WB, IHC

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Hu CD103 Purified ITGAE Monoclonal Antibody catalog # M07091-1. Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human, Monkey.

Concentration :

1 mg/ml

Gene Name :

ITGAE

Uniprot ID :

P38570

Immunogen :

HTLV-1 induced human T cell line MAPS16

Form :

Liquid

Contents :

Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Purification :

Purified by protein-A affinity chromatography

Isotype :

Mouse IgG1 kappa

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

vinculin

Synonyms :

Vinculin; Metavinculin; MV; VCL

Protein Function :

Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.

Subcellular Localization :

Cell membrane. Peripheral membrane protein. Cytoplasmic side. Sarcolemma. Cytoskeleton. Adherens junction. Focal adhesion.

Tissue Specificity :

Metavinculin is muscle-specific.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Background :

In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. It is mapped to 10q22.2. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.