Anti-Histone H3.3 H3F3A Rabbit Monoclonal Antibody | Boster M06819 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Histone H3.3 H3F3A Rabbit Monoclonal Antibody

catalog :

M06819

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EBF-8

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

M06819

Product Name :

Anti-Histone H3.3 H3F3A Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

EBF-8

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IF, IHC, ICC, WB

Application Details :

WB 1:500-1:1000 .IHC 1:500-1:1000 .ICC/IF 1:500-1:1000

Description :

Boster Bio Anti-Histone H3.3 H3F3A Rabbit Monoclonal Antibody catalog # M06819. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

H3F3A

Uniprot ID :

P84243

Immunogen :

A synthesized peptide derived from human Histone H3.3

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Histone H3.3

Synonyms :

Histone H3.3; H3F3A; H3.3A, H3F3; PP781; H3F3B; H3.3B;

Molecular Weight :

15328 MW

Protein Function :

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Subcellular Localization :

Nucleus. Chromosome.

Research Category :

ChIP’ing Antibodies, Epigenetics and Nuclear Signaling, Histones