This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-EIF2C3 AGO3 Rabbit Monoclonal Antibody
catalog :
M04191
quantity :
100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
GGF-1
reactivity :
human, mouse, rat
application :
western blot
product information
SKU :
M04191
Product Name :
Anti-EIF2C3 AGO3 Rabbit Monoclonal Antibody
Size :
100 µl
Clonality :
Monoclonal
Clone Number :
GGF-1
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Application(s) :
WB
Application Details :
WB 1:1000-1:2000
Description :
Boster Bio Anti-EIF2C3 AGO3 Rabbit Monoclonal Antibody catalog # M04191. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Concentration :
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Gene Name :
AGO3
Uniprot ID :
Q9H9G7
Immunogen :
A synthesized peptide derived from human EIF2C3
Form :
Liquid
Contents :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification :
Affinity-chromatography
Storage :
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name :
Protein argonaute-3
Synonyms :
Protein argonaute-3 ; Argonaute3 ; hAgo3; Argonaute RISC catalytic component 3; Eukaryotic translation initiation factor 2C 3 ; eIF-2C 3 ; eIF2C 3 ; AGO3; EIF2C3;
Molecular Weight :
97360 MW
Protein Function :
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.
Subcellular Localization :
Cytoplasm, P-body.
Research Category :
DNA / RNA, Epigenetics and Nuclear Signaling, RNA Processing
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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