Anti-ILK/Integrin Linked Ilk Rabbit Monoclonal Antibody

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-ILK/Integrin Linked Ilk Rabbit Monoclonal Antibody

catalog :

M02932

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

FHE-9

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M02932

Product Name :

Anti-ILK/Integrin Linked Ilk Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

FHE-9

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Flow Cytometry, IP, IF, IHC, ICC, WB

Application Details :

WB 1:1000-1:5000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .IP 1:50 .Flow Cytometry 1:50

Description :

Boster Bio Anti-ILK/Integrin Linked Ilk Rabbit Monoclonal Antibody catalog # M02932. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

ILK

Uniprot ID :

Q13418

Immunogen :

A synthesized peptide derived from human ILK

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Integrin-linked protein kinase

Synonyms :

Integrin-linked protein kinase; 2.7.11.1; 59 kDa serine/threonine-protein kinase; ILK-1; ILK-2; p59ILK; ILK; ILK1, ILK2;

Molecular Weight :

51419 MW

Protein Function :

Receptor-proximal protein kinase regulating integrin- mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Subcellular Localization :

Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cytoplasm, myofibril, sarcomere.

Tissue Specificity :

Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.

Research Category :

Protein Phosphorylation, Signal Transduction, Tyrosine Kinases