Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody | Boster M02902 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody

catalog :

M02902

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ASC-1

The same clone is also sold as:

Invitrogen: MA5-28565
Abcam: ab228425
BioLegend: 343802, 343803, 343808
Exbio: 11-137-C025, 11-137-C100, 1P-137-T100, 1P-137-T025

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M02902

Product Name :

Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

ASC-1

Host :

Mouse

Reactivity :

Human

Application(s) :

Flow Cytometry, IP, WB, IHC

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody catalog # M02902. Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

ITGA3

Uniprot ID :

P26006

Immunogen :

Human SSC-9 cell line (squamous cell carcinoma)

Form :

Liquid

Contents :

Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Purification :

Purified by protein-A affinity chromatography

Isotype :

Mouse IgG1 kappa

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

PR/SET domain 5

Synonyms :

PR domain zinc finger protein 5; PR domain-containing protein 5; PRDM5; PFM2

Protein Function :

Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May cause G2/M arrest and apoptosis in cancer cells.

Subcellular Localization :

Nucleus.

Tissue Specificity :

Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and ICC.

Background :

PR domain zinc finger protein 5 is a protein that in humans is encoded by the PRDM5 gene. It is mapped to 4q27. The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis.