Anti-PSMA FOLH1 Rabbit Monoclonal Antibody | Boster M02846 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-PSMA FOLH1 Rabbit Monoclonal Antibody

catalog :

M02846

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BBD-6

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

product information

SKU :

M02846

Product Name :

Anti-PSMA FOLH1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

BBD-6

Host :

Rabbit

Reactivity :

Human

Application(s) :

IP, IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 . IP 1:50

Description :

Boster Bio Anti-PSMA FOLH1 Rabbit Monoclonal Antibody catalog # M02846. Tested in IP, IHC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

FOLH1

Uniprot ID :

Q04609

Immunogen :

A synthesized peptide derived from human PSMA

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Glutamate carboxypeptidase 2

Synonyms :

Glutamate carboxypeptidase 2; 3.4.17.21; Cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly-gamma-glutamate carboxypeptidase; FGCP; Glutamate carboxypeptidase II; GCPII; Membrane glutamate carboxypeptidase; mGCP; N-acetylated-alpha-linked acidic dipeptidase I; NAALADase I; Prostate-specific membrane antigen; PSM; PSMA; Pteroylpoly-gamma-glutamate carboxypeptidase; FOLH1; FOLH, NAALAD1, PSM, PSMA; GIG27;

Molecular Weight :

84331 MW

Protein Function :

Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

Subcellular Localization :

Cell membrane ; Single-pass type II membrane protein.

Tissue Specificity :

Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem. Also expressed in fetal liver and kidney. Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-3 is also found in normal prostate as well as in brain and liver. Isoform PSMA-9 is specifically expressed in prostate cancer.

Research Category :

Amino Acid Metabolism, Amino Acids, Cancer, Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Signal Transduction, Tumor Biomarkers