Anti-Human ARSA DyLight® 550 conjugated Antibody(monoclonal, 4C10)

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Human ARSA DyLight® 550 conjugated Antibody(monoclonal, 4C10)

catalog :

M02583-Dyl550

quantity :

50 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

DyLight 550

reactivity :

human

application :

flow cytometry

product information

SKU :

M02583-Dyl550

Product Name :

Anti-Human ARSA DyLight® 550 conjugated Antibody(monoclonal, 4C10)

Size :

50 ug/vial

Clonality :

Monoclonal

Host :

Mouse

Conjugate :

DyLight®550

Reactivity :

Human

Application(s) :

Flow Cytometry

Application Details :

Flow Cytometry, 1-3μg/1x10^6 cells

Description :

Boster Bio Anti-Human ARSA DyLight® 550 conjugated Antibody (monoclonal, 4C10) catalog # M02583-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

ARSA

Uniprot ID :

P15289

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human ARSA (454-482aa QALKQLQLLKAQLDAAVTFGPSQVARGED), different from the related mouse sequence by six amino acids.

Form :

Liquid

Contents :

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Cross-reactivity :

No cross reactivity with other proteins.

Isotype :

IgG2a

Storage :

At 2-8?C for one year from date of receipt. Protect from light. Do not freeze.

Gene Full Name :

arylsulfatase A

Synonyms :

Arylsulfatase A; ASA; Cerebroside-sulfatase; Arylsulfatase A component B; Arylsulfatase A component C; ARSA

Protein Function :

Hydrolyzes cerebroside sulfate.

Subcellular Localization :

Lysosome

Background :

Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Research Category :

Cancer, Cell Biology, Cell Death, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Organelles, Pathways And Processes, Signal Transduction, Subcellular Markers, Tags & Cell Markers