Anti-NOTCH4 Rabbit Monoclonal Antibody | Boster M02582 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-NOTCH4 Rabbit Monoclonal Antibody

catalog :

M02582

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

IOC-14

reactivity :

human, mouse

application :

western blot, flow cytometry

product information

SKU :

M02582

Product Name :

Anti-NOTCH4 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

IOC-14

Host :

Rabbit

Reactivity :

Human, Mouse

Application(s) :

Flow Cytometry, WB

Application Details :

WB 1:100-1:500 .Flow Cytometry 1:50

Description :

Boster Bio Anti-NOTCH4 Rabbit Monoclonal Antibody catalog # M02582. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

NOTCH4

Uniprot ID :

Q99466

Immunogen :

A synthesized peptide derived from human NOTCH4

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Neurogenic locus notch homolog protein 4

Synonyms :

Neurogenic locus notch homolog protein 4; Notch 4; hNotch4; Notch 4 extracellular truncation; Notch 4 intracellular domain; NOTCH4; INT3;

Molecular Weight :

209622 MW

Protein Function :

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).

Subcellular Localization :

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity :

Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.

Research Category :

Cardiogenesis, Cardiovascular, Epigenetics and Nuclear Signaling, Nuclear, Signaling Pathways, Stem Cells, Surface Molecules, Transcription, Transcription Factors/Regulators