Anti-Milk Fat Globule (Breast Epithelial Marker) Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Milk Fat Globule (Breast Epithelial Marker) Monoclonal Antibody

catalog :

M02518

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

EDM45

The same clone is also sold as:

Novus Biologicals: NBP2-44412-0.1mg, NBP2-47813-0.1mg
Abnova: MAB14358, MAB14357
Invitrogen: MA5-13556

reactivity :

human

application :

immunohistochemistry

product information

SKU :

M02518

Product Name :

Anti-Milk Fat Globule (Breast Epithelial Marker) Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

EDM45

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC

Application Details :

Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 min at RT).Immunofluorescence (1-2ug/ml)

Description :

Boster Bio Anti-Milk Fat Globule (Breast Epithelial Marker) Monoclonal Antibody catalog # M02518. Tested in IHC applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

MFGE8

Uniprot ID :

Q08431

Immunogen :

Delipidated human milk fat globule membrane preparation

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG1, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Lactadherin

Synonyms :

Lactadherin; Breast epithelial antigen BA46; HMFG; MFGM; Milk fat globule-EGF factor 8; MFG-E8; SED1; Lactadherin short form; Medin; MFGE8;

Molecular Weight :

43123 MW

Protein Function :

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.

Subcellular Localization :

Membrane ; Peripheral membrane protein. Secreted.

Tissue Specificity :

Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.

Research Category :

Angiogenesis, Apoptosis, Cancer, Cardiovascular, Cell Biology, Cell Death, Metabolism, Metabolism Processes, Pathways And Processes