Anti-14-3-3 YWHAB Rabbit Monoclonal Antibody | Boster M02431-2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-14-3-3 YWHAB Rabbit Monoclonal Antibody

catalog :

M02431-2

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

HHG-25

reactivity :

human, mouse, rat

application :

western blot

product information

SKU :

M02431-2

Product Name :

Anti-14-3-3 YWHAB Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

HHG-25

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Application Details :

WB 1:5000-1:20000

Description :

Boster Bio Anti-14-3-3 YWHAB Rabbit Monoclonal Antibody catalog # M02431-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

YWHAB

Uniprot ID :

P31946

Immunogen :

A synthesized peptide derived from human 41701

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

14-3-3 protein beta/alpha

Synonyms :

14-3-3 protein beta/alpha; Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1; 14-3-3 protein beta/alpha, N-terminally processed; YWHAB;

Molecular Weight :

28082 MW

Protein Function :

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.

Subcellular Localization :

Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Research Category :

Adapters, Cell Type Marker, Cytoplasmic, Neural Signal Transduction, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction, Signaling Pathways, Stem Cells, Synapse Marker