Anti-Hsp75 TRAP1 Rabbit Monoclonal Antibody | Boster M02426-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Hsp75 TRAP1 Rabbit Monoclonal Antibody

catalog :

M02426-1

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

IBD-20

reactivity :

human

application :

western blot, immunoprecipitation

product information

SKU :

M02426-1

Product Name :

Anti-Hsp75 TRAP1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

IBD-20

Host :

Rabbit

Reactivity :

Human

Application(s) :

WB, IP

Application Details :

WB 1:500-1:2000 .IP 1:50

Description :

Boster Bio Anti-Hsp75 TRAP1 Rabbit Monoclonal Antibody catalog # M02426-1. Tested in IP, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

TRAP1

Uniprot ID :

Q12931

Immunogen :

A synthesized peptide derived from human Hsp75

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Heat shock protein 75 kDa, mitochondrial

Synonyms :

Heat shock protein 75 kDa, mitochondrial; HSP 75; TNFR-associated protein 1; Tumor necrosis factor type 1 receptor-associated protein; TRAP-1; TRAP1; HSP75;

Molecular Weight :

80110 MW

Protein Function :

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Subcellular Localization :

Mitochondrion. Mitochondrion inner membrane. Mitochondrion matrix.

Tissue Specificity :

Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is higly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors.

Research Category :

Apoptosis, Cancer, Cell Biology, Cell Death, Chaperones, Heat Shock Proteins, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways And Processes, Protein Trafficking, Signal Transduction