Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody | Boster M02263 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody

catalog :

M02263

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EAD-1

reactivity :

human

application :

western blot, immunohistochemistry

product information

SKU :

M02263

Product Name :

Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

EAD-1

Host :

Rabbit

Reactivity :

Human

Application(s) :

IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:500-1:2000

Description :

Boster Bio Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody catalog # M02263. Tested in IHC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

ARNT

Uniprot ID :

P27540

Immunogen :

A synthesized peptide derived from human HIF-1 beta

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Aryl hydrocarbon receptor nuclear translocator

Synonyms :

Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta; ARNT; BHLHE2;

Molecular Weight :

86636 MW

Protein Function :

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Subcellular Localization :

Nucleus.

Research Category :

Cancer, Cancer Metabolism, Epigenetics and Nuclear Signaling, Metabolism, Metabolism Processes, Neural Signal Transduction, Neurology Process, Neuroscience, Pathways And Processes, Pol Ii Transcription, Polymerase Associated Factors, Response To Hypoxia, Transcription, Transcription Factors