This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-Ms CD8a Purified Monoclonal Antibody
catalog :
M02236
quantity :
0.1 mg (C100)
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
53-6.7

The same clone is also sold as:
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
product information
SKU :
M02236
Product Name :
Anti-Ms CD8a Purified Monoclonal Antibody
Size :
0.1 mg (C100)
Clonality :
Monoclonal
Clone Number :
53-6.7
Host :
Rat
Reactivity :
Mouse
Application(s) :
Flow Cytometry, IP, IHC, ICC
Application Notes :
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Description :
Boster Bio Anti-Ms CD8a Purified Monoclonal Antibody catalog # M02236. Tested in Flow Cytometry, IP, IHC, ICC applications. This antibody reacts with Mouse.
Concentration :
1 mg/ml
Gene Name :
Cd8a
Uniprot ID :
P01731
Immunogen :
Murine spleen cells
Form :
Liquid
Contents :
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purification :
Purified by protein-A affinity chromatography
Isotype :
Rat IgG2a kappa
Storage :
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Gene Full Name :
sprouty RTK signaling antagonist 4
Synonyms :
Protein sprouty homolog 4; Spry-4; SPRY4
Protein Function :
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.
Subcellular Localization :
Ruffle membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Background :
Protein sprouty homolog 4 is a protein that in humans is encoded by the SPRY4 gene. It is mapped to 5q31.3. This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants.
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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