Anti-CD276/B7 H3 Rabbit Monoclonal Antibody | Boster M02220 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD276/B7 H3 Rabbit Monoclonal Antibody

catalog :

M02220

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

ABGB-3

reactivity :

human, mouse

application :

western blot, immunoprecipitation, flow cytometry

product information

SKU :

M02220

Product Name :

Anti-CD276/B7 H3 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

ABGB-3

Host :

Rabbit

Reactivity :

Human, Mouse

Application(s) :

Flow Cytometry, IP, WB

Application Details :

WB 1:500-1:2000 .IP 1:50 .Flow Cytometry 1:200

Description :

Boster Bio Anti-CD276/B7 H3 Rabbit Monoclonal Antibody catalog # M02220. Tested in Flow Cytometry, IP, WB applications. This antibody reacts with Human, Mouse.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CD276

Uniprot ID :

Q5ZPR3

Immunogen :

A synthesized peptide derived from human CD276

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

CD276 antigen

Synonyms :

CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276; CD276; B7H3; PSEC0249, UNQ309/PRO352;

Molecular Weight :

57235 MW

Protein Function :

May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

Subcellular Localization :

Membrane ; Single-pass type I membrane protein.

Tissue Specificity :

Ubiquitous but not detectable in peripheral blood lymphocytes or granulocytes. Weakly expressed in resting monocytes. Expressed in dendritic cells derived from monocytes. Expressed in epithelial cells of sinonasal tissue. Expressed in extravillous trophoblast cells and Hofbauer cells of the first trimester placenta and term placenta.

Research Category :

Adaptive Immunity, Cancer, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage, Tumor Biomarkers