Anti-JAM1 Rabbit Monoclonal Antibody | Boster M02068 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-JAM1 Rabbit Monoclonal Antibody

catalog :

M02068

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

FOH-6

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

M02068

Product Name :

Anti-JAM1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

FOH-6

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .

Description :

Boster Bio Anti-JAM1 Rabbit Monoclonal Antibody catalog # M02068. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

F11R

Uniprot ID :

Q9Y624

Immunogen :

A synthesized peptide derived from human JAM1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Junctional adhesion molecule A

Synonyms :

Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321; F11R; JAM1, JCAM; UNQ264/PRO301;

Molecular Weight :

32583 MW

Protein Function :

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Subcellular Localization :

Cell junction, tight junction. Cell membrane ; Single-pass type I membrane protein. Localized at tight junctions of both epithelial and endothelial cells.

Research Category :

Atherosclerosis, Cardiovascular, Cell Adhesion, Cytoskeleton / Ecm, Platelets, Signal Transduction, Tight Junctions, Vascular Inflammation