Anti-Heparan Sulfate Proteoglycan (Large) / Perlecan HSPG2 Monoclonal Antibody

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Heparan Sulfate Proteoglycan (Large) / Perlecan HSPG2 Monoclonal Antibody

catalog :

M02029

quantity :

100 ug/vial

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

SPM255

The same clone is also sold as:

Novus Biologicals: NBP3-11461, NBP2-44449-0.1mg
Abnova: MAB13085, MAB13086

reactivity :

human

application :

immunohistochemistry

product information

SKU :

M02029

Product Name :

Anti-Heparan Sulfate Proteoglycan (Large) / Perlecan HSPG2 Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

SPM255

Host :

Rat

Reactivity :

Pig, Bovine, Mouse, Monkey, Human

Application(s) :

IHC

Application Details :

Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT).Immunofluorescence (0.5-1ug/ml)

Description :

Boster Bio Anti-Heparan Sulfate Proteoglycan (Large) / Perlecan HSPG2 Monoclonal Antibody catalog # M02029. Tested in IHC applications. This antibody reacts with Bovine, Human, Monkey, Mouse, Pig.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

HSPG2

Uniprot ID :

P98160

Immunogen :

Murine EHS laminin preparation

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG2a, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Basement membrane-specific heparan sulfate proteoglycan core protein

Synonyms :

Basement membrane-specific heparan sulfate proteoglycan core protein; HSPG; Perlecan; PLC; Endorepellin; LG3 peptide; HSPG2;

Molecular Weight :

468830 MW

Protein Function :

Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix, basement membrane.

Tissue Specificity :

Found in the basement membranes.

Research Category :

Angiogenesis, Cancer, Cancer Metabolism, Cardiovascular, Cytoskeleton / Ecm, Extracellular Matrix, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Lipids And Lipoproteins, Pathways And Processes, Signal Transduction