Anti-Midkine MDK Rabbit Monoclonal Antibody | Boster M01823 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Midkine MDK Rabbit Monoclonal Antibody

catalog :

M01823

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EBI-13

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M01823

Product Name :

Anti-Midkine MDK Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

EBI-13

Host :

Rabbit

Reactivity :

Human

Application(s) :

IP, IF, IHC, ICC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .IP 1:30

Description :

Boster Bio Anti-Midkine MDK Rabbit Monoclonal Antibody catalog # M01823. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

MDK

Uniprot ID :

P21741

Immunogen :

A synthesized peptide derived from human Midkine

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Midkine

Synonyms :

Midkine; MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MK1, NEGF2;

Molecular Weight :

15585 MW

Protein Function :

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions.

Research Category :

Growth And Development, Neurogenesis, Neurology Process, Neuroscience