Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody | Boster M01605 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody

catalog :

M01605

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

AHD-3

reactivity :

human

application :

western blot

product information

SKU :

M01605

Product Name :

Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

AHD-3

Host :

Rabbit

Reactivity :

Human

Application(s) :

Application Details :

WB 1:500-1:2000

Description :

Boster Bio Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody catalog # M01605. Tested in WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CCL19

Uniprot ID :

Q99731

Immunogen :

A synthesized peptide derived from human CCL19

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

C-C motif chemokine 19

Synonyms :

C-C motif chemokine 19; Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible cytokine A19; CCL19; ELC, MIP3B, SCYA19;

Molecular Weight :

10993 MW

Protein Function :

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.

Research Category :

Chemokines, G Protein Signaling, Immunology, Innate Immunity, Macrophage / Inflamm., Signal Transduction, Signaling Pathway