Anti-PTH/PTHrP-R PTH1R Monoclonal Antibody | Boster M01588-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-PTH/PTHrP-R PTH1R Monoclonal Antibody

catalog :

M01588-1

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4D2

The same clone is also sold as:

OriGene: AM06494SU-N
Abnova: MAB10307
MyBioSource: MBS850104
Novus Biologicals: NBP1-51640
Invitrogen: MA5-15676

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

M01588-1

Product Name :

Anti-PTH/PTHrP-R PTH1R Monoclonal Antibody

Size :

100 ul

Clonality :

Monoclonal

Clone Number :

4D2

Host :

Mouse

Reactivity :

Human

Application(s) :

WB, IHC, IF, ELISA

Application Details :

WB 1:500-1:2000.IHC 1:200-1:1000.IF 1:200-1:1000 ELISA 1:10000

Description :

Boster Bio Anti-PTH/PTHrP-R PTH1R Monoclonal Antibody catalog # M01588-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

PTH1R

Uniprot ID :

Q03431

Immunogen :

Purified recombinant fragment of human PTH/PTHrP-R expressed in E. Coli.

Form :

Liquid

Contents :

Ascitic fluid containing 0.03% sodium azide.

Purification :

Affinity purification

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Caspase-1

Synonyms :

Caspase-1; CASP-1; 3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; Caspase-1 subunit p20; Caspase-1 subunit p10; CASP1; IL1BC, IL1BCE;

Protein Name :

Caspase-1

Molecular Weight :

45159 MW

Protein Function :

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive (PubMed:28314590).

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.