Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259

catalog :

M01577-2

quantity :

100 uL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM259

The same clone is also sold as:

Abnova: MAB15134

reactivity :

human

application :

western blot

product information

SKU :

M01577-2

Product Name :

Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259

Size :

100 uL

Clonality :

Monoclonal

Clone Number :

RM259

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Application Details :

Western Blot (WB): 1:1000-1:2000 dilution

Description :

Boster Bio Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259 catalog # M01577-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CDH2

Uniprot ID :

P19022

Immunogen :

A peptide corresponding to Human N-Cadherin

Contents :

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Cadherin-2

Synonyms :

Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD325; CDH2; CDHN, NCAD;

Molecular Weight :

99809 MW

Protein Function :

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

Subcellular Localization :

Cell membrane ; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface. Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes.

Research Category :

Cadherins, Cell Adhesion, Cytoskeleton / Ecm, Signal Transduction