Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody | Boster M01577-1 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody

catalog :

M01577-1

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

FI-3

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

M01577-1

Product Name :

Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

FI-3

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200

Description :

Boster Bio Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody catalog # M01577-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CDH2

Uniprot ID :

P19022

Immunogen :

A synthesized peptide derived from human N Cadherin

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Cadherin-2

Synonyms :

Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD325; CDH2; CDHN, NCAD;

Molecular Weight :

99809 MW

Protein Function :

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

Subcellular Localization :

Cell membrane; Single-pass type I membrane protein.

Research Category :

Cadherins, Cell Adhesion, Cytoskeleton / Ecm, Signal Transduction