Anti-Bim BCL2L11 Rabbit Monoclonal Antibody | Boster M01552 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Bim BCL2L11 Rabbit Monoclonal Antibody

catalog :

M01552

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

CBE-2

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M01552

Product Name :

Anti-Bim BCL2L11 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

CBE-2

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IP, IF, IHC, ICC, WB

Application Details :

WB 1:500-1:1000 .IHC 1:50-1:100 .ICC/IF 1:50-1:100 .IP 1:40

Description :

Boster Bio Anti-Bim BCL2L11 Rabbit Monoclonal Antibody catalog # M01552. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

BCL2L11

Uniprot ID :

O43521

Immunogen :

A synthesized peptide derived from human Bim

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Bcl-2-like protein 11

Synonyms :

Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death; BCL2L11; BIM;

Molecular Weight :

22171 MW

Protein Function :

Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

Subcellular Localization :

Endomembrane system ; Peripheral membrane protein. Associated with intracytoplasmic membranes.

Tissue Specificity :

Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.

Research Category :

Alzheimer'S Disease, Apoptosis, Apoptotic Markers, Associated Proteins, Cancer, Cell Biology, Cell Death, Immunology, Innate Immunity, Intracellular, Invasion/Microenvironment, Macrophage / Inflamm., Mapk Pathway, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Oncoproteins, Oncoproteins/Suppressors, Pathways And Processes, Protein Phosphorylation, Ser / Thr Kinases, Signal Transduction