Anti-MAP1LC3A/Lc3A Rabbit Monoclonal Antibody | Boster M01543 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-MAP1LC3A/Lc3A Rabbit Monoclonal Antibody

catalog :

M01543

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

GCH-13

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M01543

Product Name :

Anti-MAP1LC3A/Lc3A Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

GCH-13

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IP, IHC, ICC, WB

Application Details :

WB 1:5000-1:20000 .IHC 1:50-1:200 .ICC 1:50-1:200 .IP 1:50

Description :

Boster Bio Anti-MAP1LC3A/Lc3A Rabbit Monoclonal Antibody catalog # M01543. Tested in IP, IF, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

MAP1LC3A

Uniprot ID :

Q9H492

Immunogen :

A synthesized peptide derived from human MAP1LC3A

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Microtubule-associated proteins 1A/1B light chain 3A

Synonyms :

Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha; MAP1LC3A;

Molecular Weight :

14272 MW

Protein Function :

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600).

Subcellular Localization :

Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome. LC3-II binds to the autophagic membranes.

Tissue Specificity :

Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.

Research Category :

Cancer, Cardiovascular, Cell Death, Cytoskeleton, Cytoskeleton / Ecm, Metabolism, Metabolism Processes, Microtubules, Pathways And Processes, Signal Transduction