Anti-LC3B MAP1LC3B Rabbit Monoclonal Antibody | Boster M01524 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-LC3B MAP1LC3B Rabbit Monoclonal Antibody

catalog :

M01524

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

IEC-13

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

product information

SKU :

M01524

Product Name :

Anti-LC3B MAP1LC3B Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

IEC-13

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, IP

Application Details :

WB 1:500-1:2000 .IP 1:50

Description :

Boster Bio Anti-LC3B MAP1LC3B Rabbit Monoclonal Antibody catalog # M01524. Tested in IP, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

MAP1LC3B

Uniprot ID :

Q9GZQ8

Immunogen :

A synthesized peptide derived from human LC3B

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Microtubule-associated proteins 1A/1B light chain 3B

Synonyms :

Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light chain 3 beta; MAP1LC3B; MAP1ALC3;

Molecular Weight :

14688 MW

Protein Function :

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Subcellular Localization :

Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome. LC3-II binds to the autophagic membranes. Localizes also to discrete punctae along the ciliary axoneme (By similarity).

Tissue Specificity :

Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.