Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody | Boster M01473 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody

catalog :

M01473

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EGE-1

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

M01473

Product Name :

Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

EGE-1

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200

Description :

Boster Bio Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody catalog # M01473. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

ADRBK1

Uniprot ID :

P25098

Immunogen :

A synthesized peptide derived from human GRK2

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Beta-adrenergic receptor kinase 1

Synonyms :

Beta-adrenergic receptor kinase 1; Beta-ARK-1; 2.7.11.15; G-protein coupled receptor kinase 2; ADRBK1; BARK, BARK1, GRK2;

Molecular Weight :

79574 MW

Protein Function :

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.

Subcellular Localization :

Cytoplasm. Cell membrane.

Tissue Specificity :

Expressed in peripheral blood leukocytes.

Research Category :

G Protein Signaling, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway