Anti-Cytokeratin 14 KRT14 Rabbit Monoclonal Antibody | Boster M01432-1 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Cytokeratin 14 KRT14 Rabbit Monoclonal Antibody

catalog :

M01432-1

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EEO-11

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M01432-1

Product Name :

Anti-Cytokeratin 14 KRT14 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

EEO-11

Host :

Rabbit

Reactivity :

Human

Application(s) :

IP, IF, IHC, ICC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .IP 1:50

Description :

Boster Bio Anti-Cytokeratin 14 KRT14 Rabbit Monoclonal Antibody catalog # M01432-1. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

KRT14

Uniprot ID :

P02533

Immunogen :

A synthesized peptide derived from human Cytokeratin 14

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Keratin, type I cytoskeletal 14

Synonyms :

Keratin, type I cytoskeletal 14; Cytokeratin-14; CK-14; Keratin-14; K14; KRT14;

Molecular Weight :

51561 MW

Protein Function :

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

Subcellular Localization :

Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.

Tissue Specificity :

Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.