Anti-pS2 / pNR-2 / Trefoil Factor 1 (Estrogen-Regulated Protein) TFF1 Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-pS2 / pNR-2 / Trefoil Factor 1 (Estrogen-Regulated Protein) TFF1 Monoclonal Antibody

catalog :

M01391

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPM313

The same clone is also sold as:

Abcam: ab212861
Abnova: MAB13166, MAB13165

reactivity :

human

application :

immunohistochemistry

product information

SKU :

M01391

Product Name :

Anti-pS2 / pNR-2 / Trefoil Factor 1 (Estrogen-Regulated Protein) TFF1 Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

SPM313

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC

Application Details :

Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 minutes at RT).Immunofluorescence (0.5-1ug/ml)

Description :

Boster Bio Anti-pS2 / pNR-2 / Trefoil Factor 1 (Estrogen-Regulated Protein) TFF1 Monoclonal Antibody catalog # M01391. Tested in IHC applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

TFF1

Uniprot ID :

P04155

Immunogen :

Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human pS2.

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG1, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Trefoil factor 1

Synonyms :

Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1.A; hP1.A; Protein pS2; TFF1; BCEI, PS2;

Molecular Weight :

9150 MW

Protein Function :

Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.

Subcellular Localization :

Secreted.

Tissue Specificity :

Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level).

Research Category :

Nuclear Signaling, Signal Transduction, Signaling Pathway