Anti-Cytokeratin 18 (KRT18) Monoclonal Antibody | Boster M01357 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Cytokeratin 18 (KRT18) Monoclonal Antibody

catalog :

M01357

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

C-04; same as Ks18.04

The same clone is also sold as:

Novus Biologicals: NBP2-44951-0.1mg, NBP3-11485

reactivity :

human, mouse, rat, dogs, bovine

application :

immunohistochemistry

product information

SKU :

M01357

Product Name :

Anti-Cytokeratin 18 (KRT18) Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

C-04; same as Ks18.04

Host :

Mouse

Reactivity :

Bovine, Canine, Equine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rat

Application(s) :

IHC

Application Details :

Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 min at RT).Immunofluorescence (1-2ug/ml)

Description :

Boster Bio Anti-Cytokeratin 18 (KRT18) Monoclonal Antibody catalog # M01357. Tested in IHC applications. This antibody reacts with Bovine, Canine, Equine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rat.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

KRT18

Uniprot ID :

P05783

Immunogen :

Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG1, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Keratin, type I cytoskeletal 18

Synonyms :

Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18; KRT18; CYK18; PIG46;

Molecular Weight :

48058 MW

Protein Function :

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Subcellular Localization :

Cytoplasm, perinuclear region. Nucleus, nucleolus.

Tissue Specificity :

Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.

Research Category :

Cell Type Markers, Class I, Cytoskeleton, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Intermediate Filaments, Microtubules, Signal Transduction, Structures, Tumor Associated