Anti-Hepcidin HAMP Rabbit Monoclonal Antibody | Boster M01347 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Hepcidin HAMP Rabbit Monoclonal Antibody

catalog :

M01347

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

AAHH-8

reactivity :

human

application :

western blot

product information

SKU :

M01347

Product Name :

Anti-Hepcidin HAMP Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

AAHH-8

Host :

Rabbit

Reactivity :

Human, Rat

Application(s) :

Application Details :

WB 1:500-1:2000

Description :

Boster Bio Anti-Hepcidin HAMP Rabbit Monoclonal Antibody catalog # M01347. Tested in WB applications. This antibody reacts with Human, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

HAMP

Uniprot ID :

P81172

Immunogen :

A synthesized peptide derived from human Hepcidin

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Hepcidin

Synonyms :

Hepcidin; Liver-expressed antimicrobial peptide 1; LEAP-1; Putative liver tumor regressor; PLTR; Hepcidin-25; Hepc25; Hepcidin-20; Hepc20; HAMP; HEPC, LEAP1; UNQ487/PRO1003;

Molecular Weight :

9408 MW

Protein Function :

Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).

Subcellular Localization :

Secreted.

Tissue Specificity :

Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.

Research Category :

Cancer, Cardiovascular, Cofactors, Vitamins / Minerals, Metabolism, Pathways And Processes, Serum Proteins, Signal Transduction, Vitamins / Minerals