Anti-Thrombomodulin / CD141 (Endothelial Cell Marker) Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Thrombomodulin / CD141 (Endothelial Cell Marker) Monoclonal Antibody

catalog :

M01325

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

THBD/1782

The same clone is also sold as:

Abnova: MAB15009, MAB15008

reactivity :

human

application :

immunohistochemistry

product information

SKU :

M01325

Product Name :

Anti-Thrombomodulin / CD141 (Endothelial Cell Marker) Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

THBD/1782

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC

Application Details :

Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT).Immunofluorescence (0.5-1ug/ml)

Description :

Boster Bio Anti-Thrombomodulin / CD141 (Endothelial Cell Marker) Monoclonal Antibody catalog # M01325. Tested in IHC applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

THBD

Uniprot ID :

P07204

Immunogen :

Recombinant human Thrombomodulin protein fragment (aa69-194) (exact sequence is proprietary)

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG2a, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Thrombomodulin

Synonyms :

Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM;

Molecular Weight :

60329 MW

Protein Function :

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Tissue Specificity :

Endothelial cells are unique in synthesizing thrombomodulin.

Research Category :

Cardiovascular, Stem Cells