Anti-Thrombomodulin THBD Rabbit Monoclonal Antibody | Boster M01325-1 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Thrombomodulin THBD Rabbit Monoclonal Antibody

catalog :

M01325-1

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

COO-20

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M01325-1

Product Name :

Anti-Thrombomodulin THBD Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

COO-20

Host :

Rabbit

Reactivity :

Human

Application(s) :

IP, IF, IHC, ICC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .IP 1:50 .

Description :

Boster Bio Anti-Thrombomodulin THBD Rabbit Monoclonal Antibody catalog # M01325-1. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

THBD

Uniprot ID :

P07204

Immunogen :

A synthesized peptide derived from human Thrombomodulin

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Thrombomodulin

Synonyms :

Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM;

Molecular Weight :

60329 MW

Protein Function :

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Tissue Specificity :

Endothelial cells are unique in synthesizing thrombomodulin.

Research Category :

Cardiovascular, Stem Cells