Anti-Hu CD62P Purified SELP Monoclonal Antibody | Boster M01241-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Hu CD62P Purified SELP Monoclonal Antibody

catalog :

M01241-1

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AK4

The same clone is also sold as:

BioLegend: 304935, 304949, 304919, 304922, 304930, 304920, 304940, 304941, 304902, 304931, 304947, 304914, 304928, 304939, 304936, 304929, 304908, 304921, 304938, 260364, 304944, 304910, 304903, 304933, 304937, 304948, 304926, 260362, 304943, 304905, 304927, 304942, 304925, 304932, 304916, 986402, 304951, 304906, 304918, 304904, 304945, 304924, 986404
Exbio: 1A-667-T025, T8-667-T025, 11-667-C025, 1F-667-T025, 12-667-C100, 1P-667-T100, 1B-667-C100, 1A-667-T100, 1B-667-C025, 11-667-C100, 1P-667-T025, 1F-667-T100, T8-667-T100
Santa Cruz Biotechnology: sc-19996, sc-19996 L
BD Biosciences: 551345, 555522, 555523, 550888, 555524
Invitrogen: A15728, 11-0628-42, 14-0628-82, MA1-10264, 14-0628-80, 14-0628-37, MA5-28596, 12-0628-42
Abnova: MAB10241, MAB10170
OriGene: AM26020AC-N, AM26020PU-N, AM26020LE-N, AM26020FC-N, AM26020BT-N, AM26020RP-N

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M01241-1

Product Name :

Anti-Hu CD62P Purified SELP Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

AK4

Host :

Mouse

Reactivity :

Human, Monkey

Application(s) :

Flow Cytometry, IP, WB, ICC

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Hu CD62P Purified SELP Monoclonal Antibody catalog # M01241-1. Tested in Flow Cytometry, IP, ICC, WB applications. This antibody reacts with Human, Monkey.

Concentration :

1 mg/ml

Gene Name :

SELP

Uniprot ID :

P16109

Immunogen :

Human platelets

Form :

Liquid

Contents :

Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Purification :

Purified by protein-A affinity chromatography

Isotype :

Mouse IgG1 kappa

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

ubiquitin specific peptidase 44

Synonyms :

Ubiquitin carboxyl-terminal hydrolase 44; Deubiquitinating enzyme 44; Ubiquitin thioesterase 44; Ubiquitin-specific-processing protease 44; USP44

Protein Function :

Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B (H2BK120ub1) ubiquitination.

Subcellular Localization :

Nucleus.

Tissue Specificity :

Expressed in testis. Expressed at high levels in T-cell acute lymphoblastic leukemia.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and ICC.

Background :

Ubiquitin carboxyl-terminal hydrolase 44 is an enzyme that in humans is encoded by the USP44 gene. It is mapped to 12q22. The protein encoded by this gene is a protease that functions as a deubiquitinating enzyme. The encoded protein is thought to help regulate the spindle assembly checkpoint by preventing early anaphase onset. This protein specifically deubiquitinates CDC20, which stabilizes the anaphase promoting complex/cyclosome.