Anti-Vinculin VCL Rabbit Monoclonal Antibody | Boster M01207 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Vinculin VCL Rabbit Monoclonal Antibody

catalog :

M01207

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

AIG-22

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

product information

SKU :

M01207

Product Name :

Anti-Vinculin VCL Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

AIG-22

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IP, IF, WB

Application Details :

WB 1:500-1:2000 .ICC/IF 1:50-1:200 .IP 1:50

Description :

Boster Bio Anti-Vinculin VCL Rabbit Monoclonal Antibody catalog # M01207. Tested in IP, IF, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

VCL

Uniprot ID :

P18206

Immunogen :

A synthesized peptide derived from human Vinculin

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Vinculin

Synonyms :

Vinculin; Metavinculin; MV; VCL;

Molecular Weight :

123799 MW

Protein Function :

Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.

Subcellular Localization :

Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane ; Peripheral membrane protein ; Cytoplasmic side. Cell junction, focal adhesion. Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II- dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (By similarity). Colocalizes with LIMD1 in the focal adhesions.

Tissue Specificity :

Metavinculin is muscle-specific.

Research Category :

Actin Binding Proteins, Actin Etc, Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton / Ecm, Microfilaments, Signal Transduction