Anti-Vinculin VCL Monoclonal Antibody | Boster M01207-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Vinculin VCL Monoclonal Antibody

catalog :

M01207-1

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AS1A35

reactivity :

human

application :

immunohistochemistry

product information

SKU :

M01207-1

Product Name :

Anti-Vinculin VCL Monoclonal Antibody

Size :

100 ul

Clonality :

Monoclonal

Clone Number :

AS1A35

Host :

Mouse

Reactivity :

Human

Application(s) :

IHC

Application Details :

IHC 1:500

Description :

Boster Bio Anti-Vinculin VCL Monoclonal Antibody catalog # M01207-1. Tested in IHC applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

VCL

Uniprot ID :

P18206

Immunogen :

Synthesized peptide derived from human Vinculin

Form :

Liquid

Contents :

Liquid form in PBS containing 50% glycerol, 0.5% BSA & 0.02% sodium azide.

Purification :

Vinculin (AS1A35) antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Junctional adhesion molecule A

Synonyms :

Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321; F11R; JAM1, JCAM; UNQ264/PRO301;

Protein Name :

Junctional adhesion molecule A

Molecular Weight :

32583 MW

Protein Function :

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6- PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha- L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).

Subcellular Localization :

Cell junction, tight junction

Tissue Specificity :

Expressed in endothelium, epithelium and leukocytes (at protein level).