Anti-NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Monoclonal Antibody

catalog :

M01187

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPM299

reactivity :

human

application :

immunohistochemistry

product information

sku :

M01187

status :

Enabled

name :

Anti-NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Monoclonal Antibody

category name :

Primary Antibodies, Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

NGFR

price various sizes :

20ug sample size / $99 100ug / $299 100ug+Free HRP Secondary BA1050 / $299 100ug+Free Biotin Secondary BA1001 / $299

clonality :

Monoclonal

clone number :

SPM299

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

description :

Mouse Monoclonal Antibody [Clone SPM299] antibody for P75/NGFR detection. Host: Mouse.Size: 100ug/vial. Tested applications: IF. Reactive species: Feline. P75/NGFR information: Molecular Weight: 45183 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein.

short description :

Anti-NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody

size :

100 ug/vial

sample size available :

20ug for $99, contact us for details

uniprot id :

P08138

host :

Mouse

immunogen :

NGFR from A875 melanoma cells

form :

Liquid

application details :

Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT). Immunofluorescence (1-2ug/ml)

applications :

IHC

reactivity :

Human, Monkey, Rabbit

image labels :

Formalin-fixed, paraffin-embedded human Melanoma stained withNGFR Monoclonal Antibody (SPM299).

research category :

Growth And Development, Mesenchymal Stem Cells, Neural Stem Cells, Neurology Process, Neuroscience, Stem Cells, Surface Molecules

synonyms :

Tumor necrosis factor receptor superfamily member 16;Gp80-LNGFR;Low affinity neurotrophin receptor p75NTR;Low-affinity nerve growth factor receptor;NGF receptor;p75 ICD;CD271;NGFR;TNFRSF16;

gene full name :

Tumor necrosis factor receptor superfamily member 16

molecular weight :

45183 MW

protein function :

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

subcellular localization :

Membrane; Single-pass type I membrane protein.

last modified :

2/6/19 22:57