Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody | Boster M01127 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody

catalog :

M01127

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

HBB-19

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

SKU :

M01127

Product Name :

Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

HBB-19

Host :

Rabbit

Reactivity :

Human, Rat

Application(s) :

IHC, WB

Application Details :

WB 1:1000-1:2000 .IHC 1:50-1:200

Description :

Boster Bio Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody catalog # M01127. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

SFN

Uniprot ID :

P31947

Immunogen :

A synthesized peptide derived from human 14-3-3 sigma

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

14-3-3 protein sigma

Synonyms :

14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin; SFN; HME1;

Molecular Weight :

27774 MW

Protein Function :

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

Subcellular Localization :

Cytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway.

Tissue Specificity :

Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Research Category :

Adapters, Cell Type Marker, Cytoplasmic, Neural Signal Transduction, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction, Signaling Pathways, Stem Cells, Synapse Marker