Anti-Podoplanin (PDPN) (Lymphatic Endothelial Mesothelial Marker) Monoclonal Antibody

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product summary

company name :

Boster

product type :

other

product name :

Anti-Podoplanin (PDPN) (Lymphatic Endothelial Mesothelial Marker) Monoclonal Antibody

catalog :

M01124

quantity :

100 ug/vial

product information

sku :

M01124

status :

Enabled

name :

Anti-Podoplanin (PDPN) (Lymphatic Endothelial Mesothelial Marker) Monoclonal Antibody

category name :

Primary Antibodies, Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

PDPN

price various sizes :

20ug sample size / $99 100ug / $299 100ug+Free HRP Secondary BA1050 / $299 100ug+Free Biotin Secondary BA1001 / $299 100ug no BSA & Azide / $299

clonality :

Monoclonal

clone number :

PDPN/1433

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

description :

Anti-Podoplanin (PDPN) (Lymphatic Endothelial Mesothelial Marker) Antibody

short description :

Anti-Podoplanin (PDPN) (Lymphatic Endothelial Mesothelial Marker) Antibody

size :

100 ug/vial

sample size available :

20ug for $99, contact us for details

uniprot id :

Q86YL7

host :

Mouse

immunogen :

Recombinant human Podoplanin (PDPN) protein fragment (aa24-126) (exact sequence is proprietary)

form :

Liquid

storage :

Antibody with azide - store at 2 to 8 Â°C. Antibody without azide - store at -20 to -80 Â°C. Antibody is stable for 24 months. Non-hazardous.

application details :

Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT). Immunofluorescence (0.5-1ug/ml)

applications :

IHC

reactivity :

Human

image labels :

Formalin-fixed, paraffin-embedded human Cervix stained withPodoplanin Monoclonal Antibody (PDPN/1433)

research category :

Angiogenesis, Cardiovascular, Cell Type Markers, Tags & Cell Markers, Vasculature

synonyms :

Podoplanin;Aggrus;Glycoprotein 36;Gp36;PA2.26 antigen;T1-alpha;T1A;PDPN ;GP36 ;PSEC0003, PSEC0025;

gene full name :

Podoplanin

molecular weight :

16698 MW

protein function :

May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.

subcellular localization :

Membrane ; Single-pass type I membrane protein . Cell projection, filopodium membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell projection, microvillus membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles.

tissue specificity :

Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.

last modified :

2/15/19 23:36