This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-Ms CD41 Purified Itga2b Monoclonal Antibody
catalog :
M01102-2
quantity :
0.1 mg (C100)
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MWReg30

The same clone is also sold as:
reactivity :
mouse
application :
immunohistochemistry, immunoprecipitation, flow cytometry
product information
SKU :
M01102-2
Product Name :
Anti-Ms CD41 Purified Itga2b Monoclonal Antibody
Size :
0.1 mg (C100)
Clonality :
Monoclonal
Clone Number :
MWReg30
Host :
Rat
Reactivity :
Mouse
Application(s) :
Flow Cytometry, IP, IHC, ELISA
Description :
Boster Bio Anti-Ms CD41 Purified Itga2b Monoclonal Antibody catalog # M01102-2. Tested in ELISA, Flow Cytometry, IP, IHC applications. This antibody reacts with Mouse.
Concentration :
1 mg/ml
Gene Name :
Itga2b
Uniprot ID :
Q9QUM0
Immunogen :
Murine platelets
Form :
Liquid
Contents :
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purification :
Purified by protein-G affinity chromatography
Isotype :
Rat IgG1 kappa
Storage :
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Gene Full Name :
Baculoviral IAP repeat-containing protein 5
Synonyms :
Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin; BIRC5; API4, IAP4;
Protein Name :
Baculoviral IAP repeat-containing protein 5
Molecular Weight :
16389 MW
Protein Function :
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (PubMed:9859993, PubMed:21364656, PubMed:20627126). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (PubMed:16322459). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules (PubMed:20826784). Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis (PubMed:20929775). The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (PubMed:18591255). May counteract a default induction of apoptosis in G2/M phase (PubMed:9859993). The acetylated form represses STAT3 transactivation of target gene promoters (PubMed:20826784). May play a role in neoplasia (PubMed:10626797). Inhibitor of CASP3 and CASP7 (PubMed:21536684). Isoform 2 and isoform 3 do not appear to play vital roles in mitosis (PubMed:12773388, PubMed:16291752). Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform (PubMed:10626797).
Subcellular Localization :
Cytoplasm
Tissue Specificity :
Expressed only in fetal kidney and liver, and to lesser extent, lung and brain (PubMed:10626797). Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas (PubMed:14741722, PubMed:16329164). Also expressed in various renal cell carcinoma cell lines (PubMed:10626797). Expressed in cochlea including the organ of Corti, the lateral wall, the interdental cells of the Limbus as well as in Schwann cells and cells of the cochlear nerve and the spiral ganglions (at protein level). Not expressed in cells of the inner and outer sulcus or the Reissner's membrane (at protein level) (PubMed:21364656, PubMed:20627126).
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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