Anti-SCARB1/Sr Bi Rabbit Monoclonal Antibody | Boster M01093 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-SCARB1/Sr Bi Rabbit Monoclonal Antibody

catalog :

M01093

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

CGE-19

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

M01093

Product Name :

Anti-SCARB1/Sr Bi Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

CGE-19

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200

Description :

Boster Bio Anti-SCARB1/Sr Bi Rabbit Monoclonal Antibody catalog # M01093. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

SCARB1

Uniprot ID :

Q8WTV0

Immunogen :

A synthesized peptide derived from human Scavenging Receptor SR-BI

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Scavenger receptor class B member 1

Synonyms :

Scavenger receptor class B member 1; SRB1; CD36 and LIMPII analogous 1; CLA-1; CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; SR-BI; CD36; SCARB1; CD36L1, CLA1;

Molecular Weight :

60878 MW

Protein Function :

Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high density lipoproteins (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins (By similarity). Necessary for selective HDL-cholesterol uptake (PubMed:26965621). Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate (By similarity).

Subcellular Localization :

Cell membrane ; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.

Tissue Specificity :

Widely expressed.

Research Category :

Cancer, Cancer Metabolism, Cardiovascular, Cholesterol Metabolism, Host Virus Interaction, Interspecies Interaction, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Lipids / Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Lipids And Lipoproteins, Microbiology, Pathways And Processes, Signal Transduction