Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody | Boster M01080 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody

catalog :

M01080

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MX-49.129.5

The same clone is also sold as:

OriGene: AM50244PU-S, AM50244PU-T
Santa Cruz Biotechnology: sc-5275
MyBioSource: MBS438072
Abcam: ab193349, ab205540
Novus Biologicals: NBP2-34689-0.1mg, NBP2-32830-0.1mg
Abnova: MAB14212

reactivity :

human

application :

flow cytometry

product information

SKU :

M01080

Product Name :

Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

MX-49.129.5

Host :

Mouse

Reactivity :

Human, Mouse

Application(s) :

Flow Cytometry

Application Details :

User need to optimize the dilution ratio for this antibody

Description :

Boster Bio Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody catalog # M01080. Tested in Flow Cytometry applications. This antibody reacts with Human, Mouse.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CD63

Uniprot ID :

P08962

Immunogen :

Full length CD63 of human origin

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG1, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

CD63 antigen

Synonyms :

CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD63; CD63; MLA1, TSPAN30;

Molecular Weight :

25637 MW

Protein Function :

Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

Subcellular Localization :

Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endosome, multivesicular body. Melanosome. Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. Detected in a subset of pre-melanosomes. Detected on intralumenal vesicles (ILVs) within multivesicular bodies.

Tissue Specificity :

Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.

Research Category :

Cancer, Cardiovascular, Cell Adhesion, Cell Type Markers, Immunology, Invasion/Microenvironment, Platelets, Tags & Cell Markers, Tumor Antigens, Tumor Associated, Tumor Biomarkers