Anti-pro Caspase 7 CASP7 Rabbit Monoclonal Antibody | Boster M01044 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-pro Caspase 7 CASP7 Rabbit Monoclonal Antibody

catalog :

M01044

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

HOI-3

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

M01044

Product Name :

Anti-pro Caspase 7 CASP7 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

HOI-3

Host :

Rabbit

Reactivity :

Human

Application(s) :

IF, IHC, ICC, WB

Application Details :

WB 1:500-1:1000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200

Description :

Boster Bio Anti-pro Caspase 7 CASP7 Rabbit Monoclonal Antibody catalog # M01044. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CASP7

Uniprot ID :

P55210

Immunogen :

A synthesized peptide derived from human pro Caspase 7

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Caspase-7

Synonyms :

Caspase-7; CASP-7; 3.4.22.60; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3; Caspase-7 subunit p20; Caspase-7 subunit p11; CASP7; MCH3;

Molecular Weight :

34277 MW

Protein Function :

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly- 217' bond. Overexpression promotes programmed cell death.

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.

Research Category :

Apoptosis, Apoptotic Markers, Cancer, Caspases Etc, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways And Processes, Proteolysis / Ubiquitin, Proteolytic Enzymes