Anti-S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody

catalog :

M00979

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SH-B1

The same clone is also sold as:

Invitrogen: MA5-32985
OriGene: DM111, DM111-05
MilliporeSigma: S2532
Abcam: ab218957
Abnova: MAB3572, MAB12455

reactivity :

human

application :

immunohistochemistry

product information

SKU :

M00979

Product Name :

Anti-S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

SH-B1

Host :

Mouse

Reactivity :

201, Bovine, Rat, Rabbit, Human

Application(s) :

IHC

Application Details :

Immunofluorescence (1-2ug/ml)

Description :

Boster Bio Anti-S100B (Astrocyte and Melanoma Marker) Monoclonal Antibody catalog # M00979. Tested in IHC applications. This antibody reacts with Bovine, Human, Rabbit, Rat.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

S100B

Uniprot ID :

P04271

Immunogen :

Purified bovine brain S100 protein

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG1, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Protein S100-B

Synonyms :

Protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B; S100B;

Molecular Weight :

10713 MW

Protein Function :

Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Subcellular Localization :

Cytoplasm. Nucleus.

Tissue Specificity :

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

Research Category :

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling, Neural Stem Cells, Stem Cells