Anti-S100B/S100 Beta Rabbit Monoclonal Antibody | Boster M00979-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-S100B/S100 Beta Rabbit Monoclonal Antibody

catalog :

M00979-1

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BCB-19

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M00979-1

Product Name :

Anti-S100B/S100 Beta Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

BCB-19

Host :

Rabbit

Reactivity :

Goat, Human, Mouse, Rat

Application(s) :

IP, IF, IHC, ICC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .IP 1:50

Description :

Boster Bio Anti-S100B/S100 Beta Rabbit Monoclonal Antibody catalog # M00979-1. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Goat, Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

S100B

Uniprot ID :

P04271

Immunogen :

A synthesized peptide derived from human S100B

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Protein S100-B

Synonyms :

Protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B; S100B;

Molecular Weight :

10713 MW

Protein Function :

Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Subcellular Localization :

Cytoplasm. Nucleus.

Tissue Specificity :

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

Research Category :

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling, Neural Stem Cells, Stem Cells