Anti-HSPA5 Antibody | Boster M00955-3 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-HSPA5 Antibody

catalog :

M00955-3

quantity :

50 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

monoclonal

reactivity :

human

application :

western blot

product information

SKU :

M00955-3

Product Name :

Anti-HSPA5 Antibody

Size :

50 ul

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Application(s) :

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-HSPA5 Antibody catalog # M00955-3. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Gene Name :

HSPA5

Uniprot ID :

P11021

Immunogen :

This HSPA5 antibody is generated from a mouse immunized with a recombinant protein between 420-654 amino acids from human HSPA5.

Contents :

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Isotype :

IgG1,k

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

Bone morphogenetic protein receptor type II or BMPR2 is a serine/threonine receptor kinase. This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.