Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody | Boster M00938 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody

catalog :

M00938

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

CGH-16

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

SKU :

M00938

Product Name :

Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

CGH-16

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200

Description :

Boster Bio Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody catalog # M00938. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

PTPN6

Uniprot ID :

P29350

Immunogen :

A synthesized peptide derived from human SHP1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Tyrosine-protein phosphatase non-receptor type 6

Synonyms :

Tyrosine-protein phosphatase non-receptor type 6; 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1; PTPN6; HCP, PTP1C;

Molecular Weight :

67561 MW

Protein Function :

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

Subcellular Localization :

Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1.

Tissue Specificity :

Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.

Research Category :

Cancer, Cell Biology, Cell Cycle, Developmental Biology, G Protein Signaling, Kinases/Phosphatases, Organogenesis, Signal Transduction, Signaling Pathway