Anti-APAF1 Rabbit Monoclonal Antibody | Boster M00889 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-APAF1 Rabbit Monoclonal Antibody

catalog :

M00889

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BHF-1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

M00889

Product Name :

Anti-APAF1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

BHF-1

Host :

Rabbit

Reactivity :

Human, Mouse

Application(s) :

IF, IHC, ICC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200

Description :

Boster Bio Anti-APAF1 Rabbit Monoclonal Antibody catalog # M00889. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

APAF1

Uniprot ID :

O14727

Immunogen :

A synthesized peptide derived from human APAF1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Apoptotic protease-activating factor 1

Synonyms :

Apoptotic protease-activating factor 1; APAF-1; APAF1; KIAA0413;

Molecular Weight :

141840 MW

Protein Function :

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.

Research Category :

Apoptosis, Apoptotic Markers, Cancer, Cell Biology, Cell Death, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways And Processes