Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody | Boster M00829 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody

catalog :

M00829

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

BDC-12

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M00829

Product Name :

Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

BDC-12

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Flow Cytometry, IP, IF, IHC, ICC, WB

Application Details :

WB 1:10000-1:20000 .IHC 1:50-1:100 .ICC/IF 1:50-1:100 .IP 1:30 .Flow Cytometry 1:50 .

Description :

Boster Bio Anti-LRP1/Lrp 1 Cluster Ii Rabbit Monoclonal Antibody catalog # M00829. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

LRP1

Uniprot ID :

Q07954

Immunogen :

A synthesized peptide derived from human LRP1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Prolow-density lipoprotein receptor-related protein 1

Synonyms :

Prolow-density lipoprotein receptor-related protein 1; LRP-1; Alpha-2-macroglobulin receptor; A2MR; Apolipoprotein E receptor; APOER; CD91; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; LRP-85; Low-density lipoprotein receptor-related protein 1 515 kDa subunit; LRP-515; Low-density lipoprotein receptor-related protein 1 intracellular domain; LRPICD; LRP1; A2MR, APR;

Molecular Weight :

504606 MW

Protein Function :

Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.

Subcellular Localization :

Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit.

Tissue Specificity :

Most abundant in liver, brain and lung.

Research Category :

Alzheimer'S Disease, Apoptosis, Atherosclerosis, Cancer, Cardiovascular, Cell Biology, Cell Death, Cholesterol Metabolism, Heart Disease, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Lipids / Lipoproteins, Metabolic Signaling Pathways, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Obesity, Pathways And Processes, Serum Proteins, Signal Transduction